North Carolina

Can a North Carolina NP prescribe medication independently?

Chris Turitzin
Updated
December 9, 2025

A North Carolina NP cannot prescribe medication independently. Prescriptive authority is exercised under a collaborative practice agreement with a supervising physician1, and an NP may prescribe only when the supervising physician has provided written instructions and periodic review2; any NP prescription is deemed authorized by the supervising physician3.

Key requirements include:

  • The collaborative practice agreement must list the drugs, devices, treatments, tests, and procedures the NP may prescribe and perform at each practice site4.
  • If a needed drug or device is not listed, the NP may prescribe it only on a specific order from the supervising or back-up physician, documented in the patient record5.
  • For controlled substances (Schedules II–V), prescribing must be established in the agreement; the NP must have a DEA number and the supervising physician must hold the same or greater schedules6.

For certain targeted controlled substances used in pain-management settings for more than 30 days, the NP must personally consult the supervising physician before prescribing and at least every 90 days thereafter7. North Carolina further defines “consult” as a documented, meaningful communication sufficient for the supervising physician to determine the prescription is medically indicated8.

Citations

  1. North Carolina Administrative Code §36.0804 (a)(4)
  2. North Carolina General Statutes §90-18.2 (b)(4)
  3. North Carolina General Statutes §90-18.2 (e)
  4. North Carolina Administrative Code §36.0810 (2)(c-d)
  5. North Carolina Administrative Code §36 .0809 (a)(3)(A-B)
  6. North Carolina Administrative Code §36 .0809 (b)(2)(A-C)
  7. North Carolina General Statutes §90-18.2 (a)(5)
  8. North Carolina Administrative Code §36.0816
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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