Can an NP prescribe Codeine in Florida?

Yes, but with formulation-specific limits — a Florida NP may prescribe codeine when the NP is authorized and the specific codeine product’s schedule supports the prescription. The NP must have the required education, training, experience, and protocol or qualifying autonomous primary-care authority, plus qualifying graduate education and DEA registration. Codeine’s controlled-substance schedule varies by formulation: codeine itself is Schedule II, while qualifying limited-quantity combination products may be Schedule III or Schedule V.¹

For a Schedule II codeine product, Florida generally limits an APRN prescription to a 7-day supply.² If prescribed as an acute-pain Schedule II opioid, the default limit is 3 days unless the documented and labeled 7-day exception is met.³ Schedule III or V codeine combination products are not subject to the APRN-specific Schedule II cap,² but the product’s schedule and concentration should be confirmed before prescribing.¹

Florida’s PDMP review requirement generally applies before prescribing opioid-containing codeine products unless a statutory exception applies.⁴