Pennsylvania

Can an NP prescribe Oxycodone in Pennsylvania?

Chris Turitzin
•
Updated
September 1, 2026

Yes — Pennsylvania CRNPs may prescribe oxycodone, a Schedule II opioid, if they have current prescriptive authority approval, prescribe within their specialty and physician prescriptive authority collaborative agreement identifying Schedule II authority, and the Schedule II prescription is limited to a 30-day supply.412 They also must have at least 45 hours of advanced pharmacology coursework for prescriptive authority approval.

For controlled-substance prescribing, the CRNP must have DEA registration and comply with applicable controlled-substance prescribing standards, including Safe Emergency Prescribing Act requirements for emergency, urgent care, or observation settings.3 Pennsylvania also requires a PDMP query each time an opioid drug product is prescribed.5

CRNPs may not prescribe Schedule I controlled substances and may not delegate prescriptive authority.

Citations

  1. 49 Pa. Code §21.283(a); 49 Pa. Code §21.285
  2. 49 Pa. Code §21.284(d)(1)
  3. 49 Pa. Code §21.284b
  4. 35 P.S. §780-104(2)(i)
  5. Pennsylvania Department of Health PDMP Prescriber Q&A
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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