Can an NP prescribe Semaglutide in North Carolina?

Yes — North Carolina NPs who have active NP approval with prescriptive authority may prescribe semaglutide, a non-controlled medication, when it is within their population focus, education, national certification, competence, and collaborative practice agreement.¹²

North Carolina NP approval includes prescriptive authority for legend drugs within the NP’s scope, education, and national certification.¹ The collaborative practice agreement must identify the applicable drug categories and describe how the supervising physician will be continuously available for supervision, consultation, collaboration, referral, and evaluation.²

Because semaglutide is not controlled, this prescribing question turns on North Carolina’s legend-drug and collaborative-practice rules rather than controlled-substance prescribing requirements; controlled-substance DEA registration, CSRS review, and STOP Act opioid limits do not apply to noncontrolled semaglutide.