Can an NP prescribe Suboxone in Florida?

Yes — Florida NPs can prescribe Suboxone (buprenorphine/naloxone), a Schedule III medication, for opioid use disorder when authorized under Florida APRN law and registered with DEA for Schedule III authority.¹²³ Florida’s rule ties controlled-substance prescribing to the APRN’s education, training, experience, qualifying graduate education for controlled-substance prescribing, and applicable protocol or qualifying autonomous primary-care authority.¹

The former federal DATA 2000/X-waiver and patient-limit framework no longer applies to buprenorphine prescribing, but the NP must maintain the required DEA registration and satisfy applicable DEA training requirements.³ Florida also generally requires PDMP review before prescribing Suboxone unless a statutory exception applies.⁴ This answer concerns office-based buprenorphine prescribing and does not equate Suboxone with methadone dispensing through an opioid treatment program. Telehealth prescribing requirements require a separate federal and state analysis.