
Yes — Pennsylvania CRNPs may prescribe Suboxone (buprenorphine/naloxone), a Schedule III medication, when they have current prescriptive authority approval, including the required 45 hours of advanced pharmacology coursework, prescribe within their specialty under a physician prescriptive authority collaborative agreement, and the agreement identifies Schedule III authority.123
For Schedule III or IV controlled substances, Pennsylvania limits CRNP prescriptions to up to a 90-day supply as identified in the collaborative agreement.2 Federal law no longer requires a DATA 2000/X-waiver or patient-limit framework for buprenorphine, but the practitioner must have current DEA registration including Schedule III authority and satisfy applicable DEA registration training requirements.4 Pennsylvania PDMP query duties also apply when required, including for opioid drug product prescriptions.
This answer concerns office-based buprenorphine prescribing; telehealth prescribing requires a separate federal and state analysis. Pennsylvania CRNP rules reserve methadone treatment orders to physicians.5