
Yes — North Carolina NPs may prescribe tirzepatide when prescribing is within the NP's population focus, education, national certification, competence, and collaborative practice agreement.12Tirzepatide is not controlled, so controlled-substance DEA registration, CSRS review, and STOP Act opioid limits do not apply.
The NP must have active North Carolina NP approval with prescriptive authority, and the collaborative practice agreement must identify the applicable drug categories the NP may prescribe. The agreement also must describe the supervising physician's continuous availability for supervision, consultation, collaboration, referral, and evaluation.2