
Yes — Pennsylvania CRNPs may prescribe tirzepatide, which is not controlled, if they have current prescriptive authority approval and the prescription is within their specialty and physician prescriptive authority collaborative agreement.1
The collaborative agreement must support the applicable drug categories, and prescriptive authority approval requires at least 45 hours of advanced pharmacology coursework.12 Because tirzepatide is not a controlled substance for this analysis, Pennsylvania’s CRNP Schedule II and Schedule III/IV limits do not apply.3 A Pennsylvania CRNP may not delegate prescriptive authority.