
Yes — California nurse practitioners may prescribe tramadol, a Schedule IV opioid, when they have controlled-substance furnishing authority, DEA registration, and comply with the applicable California practice pathway.12
For NPs using standardized procedures, California controlled-substance furnishing authority may include Schedule II–V drugs only when the drug is authorized and specified in the standardized procedure.1 An NP authorized to furnish controlled substances must also register with the DEA.2
Qualifying California NPs practicing under Sections 2837.103 or 2837.104 may prescribe controlled substances without standardized procedures when that statutory pathway applies.3 Schedule II–IV prescribing also generally requires CURES review before the first prescription and periodically if continued, unless an exemption applies.4 NPs must also practice within their education, training, competence, and scope.
This answer does not address separate opioid-specific, pain-management, telehealth, payer, or facility policy requirements.