North Carolina

Can an NP prescribe Tramadol in North Carolina?

Chris Turitzin
•
Updated
September 8, 2026

Yes — North Carolina nurse practitioners may prescribe tramadol, a Schedule IV controlled substance,3 when the prescription is within the NP's population focus, education, national certification, competence, and scope and is authorized by the collaborative practice agreement.12

For tramadol prescribing, the NP must have North Carolina NP approval with controlled-substance prescriptive authority, DEA authority, and a primary supervising physician whose controlled-substance authority is at least equal to the NP's DEA registration.2

Controlled-substance prescriptions must include the NP's DEA number and be documented in the patient record.

North Carolina NPs may not prescribe controlled substances for themselves, their supervising physician, immediate family members, household members, or intimate partners.

The STOP Act targeted-controlled-substance limits cited by the Board focus on Schedule II and III opioids and narcotics, so those Schedule II/III rules are not a general Schedule IV tramadol limit.4

Citations

  1. North Carolina Board of Nursing, Nurse Practitioner Scope of Practice
  2. 21 NCAC 36 .0809(b)(2)
  3. DEA Controlled Substance Schedules; 21 C.F.R. §1308.14
  4. North Carolina Board of Nursing CSRS FAQ; N.C. Gen. Stat. §90-106(a)
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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