North Carolina

What must be in a North Carolina NP collaborative practice agreement?

Chris Turitzin
Updated
March 6, 2026

A North Carolina NP collaborative practice agreement must, at minimum, list the drugs, devices, medical treatments, tests, and procedures the NP may use at each practice site, and include a pre-determined plan for emergency services1. The agreement is the arrangement that ensures continuous availability between the NP and supervising physician for supervision, consultation, collaboration, referral, and evaluation of the NP’s care2.

Administrative requirements include:

  • The signed agreement must be maintained at the practice site by both the supervising physician and the NP3.
  • The agreement must be reviewed at least annually, with the review acknowledged by a dated signature sheet signed by both parties and available for inspection by either Board4.

If the NP will prescribe controlled substances, the agreement must establish that authority and the NP must meet additional requirements (e.g., have a DEA number; the physician must hold the same or higher schedules)5. Prescribing a drug or device not included in the agreement is allowed only on a specific written or verbal order from a supervising physician, documented in the patient record and signed by both the NP and physician6.

Citations

  1. 21 N.C. Admin. Code 36 .0810 (2)(c)-(d)
  2. 21 N.C. Admin. Code 36 .0801 (4)
  3. 21 N.C. Admin. Code 36 .0810 (2)(a)
  4. 21 N.C. Admin. Code 36 .0810 (2)(b)
  5. 21 N.C. Admin. Code 36 .0809 (b)(2)(A)-(C)
  6. 21 N.C. Admin. Code 36 .0809 (a)(3)(A)-(B)
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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