Pennsylvania

What schedule drugs can an NP prescribe in Pennsylvania?

Chris Turitzin
Updated
March 6, 2026

In Pennsylvania, the schedule drugs a nurse practitioner (CRNP) can prescribe include certain controlled substances. A CRNP may prescribe Schedule II controlled substances for up to a 30-day supply and Schedule III or IV controlled substances for up to a 90-day supply, as identified in the prescriptive authority collaborative agreement1. CRNPs are prohibited from prescribing or dispensing Schedule I drugs2.

Controlled-substance prescribing requires DEA registration3, and the prescription must include the CRNP’s National Provider Identifier (NPI)4. For emergencies, an oral prescription for a Schedule II drug must be followed by a written prescription delivered to the pharmacist within 72 hours5.

All controlled-substance prescribing occurs within the CRNP’s specialty and prescriptive authority collaborative agreement6, and CRNPs must meet minimum standards such as conducting an initial evaluation, counseling the patient, and documenting the drug name, strength, quantity, and date in the patient’s record7.

Citations

  1. 49 Pa. Code §21.284(d)(1)-(2)
  2. 49 Pa. Code §21.284(c)(5)
  3. 49 Pa. Code §21.284b(a)
  4. 49 Pa. Code §21.284a(b)(2)
  5. 49 Pa. Code §21.284b(b)(5)
  6. 49 Pa. Code §21.283(a)
  7. 49 Pa. Code §21.284b(b)(1)-(4)
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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