In Illinois, a nurse practitioner can prescribe medication independently only after obtaining full practice authority1. Until then, prescriptive authority must be delegated under a written collaborative agreement with a collaborating physician23.
With full practice authority, an APRN may prescribe legend drugs and Schedule II–V controlled substances; however, benzodiazepines or Schedule II narcotics require monthly physician consultation documented in the Prescription Monitoring Program1.
Without full practice authority, prescriptive authority is delegated via the collaborative agreement. Key requirements include:
- The collaborating physician may delegate non-controlled and controlled prescribing to the APRN3.
- The APRN must obtain a mid-level practitioner controlled substance license and DEA registration4, and the collaborating physician must also hold an Illinois controlled substances license and DEA registration5.
- Schedule II delegation is limited and must identify specific drugs by oral/topical/transdermal route, be capped at a 30-day supply with continuation only after prior physician approval, include monthly case discussions, and meet specified education requirements6.
- The collaborating physician must file notice of delegation with the Department and the PMP7, and all APRN prescriptions must include the collaborating physician’s name8.