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Can a Ohio NP prescribe controlled substances?
Ohio
Nurse Practitioner Collaboration

Can a Ohio NP prescribe controlled substances?

Chris Turitzin
•
Updated
December 9, 2025

An Ohio NP can prescribe controlled substances. In Ohio, APRNs may prescribe Schedules III–V and, under narrow conditions, certain Schedule II medications1.

Schedule II prescribing is limited to patients with a terminal condition, only after a physician has initiated the prescription, and for no more than a single seventy-two (72) hour supply1.

Prescribing must occur within a standard care arrangement that includes defined prescribing parameters, provisions for Schedule II use, and processes such as OARRS review34. An NP’s prescriptive authority may not exceed that of the collaborating physician2, and special statutory and regulatory requirements apply to opioids and to opioid analgesics for minors567.

Citations

  1. 2024 Ohio Revised Code §4723.481 (C)(1)(a–c)
  2. 2024 Ohio Revised Code §4723.481 (B)
  3. 2024 Ohio Revised Code §4723.431 (B)(1–5)
  4. Ohio Administrative Code Rule 4723-8-04 (D)(1–11)
  5. 2024 Ohio Revised Code §4723.481 (E)
  6. Ohio Administrative Code §4723-9 et seq.
  7. 2024 Ohio Revised Code §3719.061
Chris Turitzin
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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Disclaimer: The regulatory research, summaries, and tools provided by Single Aim, LLC are for informational and educational purposes only and do not constitute legal advice. While we strive to ensure accuracy, healthcare laws vary by state and may change over time. You should always consult a licensed attorney familiar with healthcare regulations in your specific state before making decisions related to you clinical and operational needs for compliance. Single Aim is not a law firm and does not provide legal representation. Use of our materials does not create an attorney-client relationship.

Need legal guidance? We recommend contacting a licensed healthcare attorney in your state or using professional associations such as the American Health Law Association (AHLA) or your state’s medical or nursing board for referrals.