Pennsylvania

Can a Pennsylvania NP prescribe controlled substances without supervision?

Chris Turitzin
Updated
March 5, 2026

A Pennsylvania CRNP cannot prescribe controlled substances without supervision. CRNPs may prescribe controlled substances only when acting in collaboration with a physician under a prescriptive authority collaborative agreement—not independently12. The agreement must also specify physician involvement, including how often the physician will personally see patients3.

When permitted, controlled-substance prescribing is limited to a 30‑day supply for Schedule II and a 90‑day supply for Schedules III–IV, as identified in the agreement4. CRNPs must first obtain DEA registration5, include their NPI on controlled-substance prescriptions6, and may not prescribe Schedule I drugs7; they must also meet minimum evaluation, counseling, and documentation standards for controlled substances8.

Citations

  1. 49 Pa. Code § 21.283(a)
  2. 49 Pa. Code § 21.251
  3. 49 Pa. Code § 21.285(a)(4)
  4. 49 Pa. Code § 21.284(d)(1)-(2)
  5. 49 Pa. Code § 21.284b(a)
  6. 49 Pa. Code § 21.284a(b)(2)
  7. 49 Pa. Code § 21.284(c)(5)
  8. 49 Pa. Code § 21.284b(b)(1)-(4)
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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