
In most cases, no — Texas NPs generally cannot prescribe hydrocodone, a Schedule II opioid, unless the prescription fits one of Texas’s narrow Schedule II exceptions.
Texas APRN controlled-substance authority generally covers Schedule III–V drugs, not general Schedule II opioid prescribing.1 For hydrocodone, Schedule II delegation may be allowed only in hospital facility-based practice or for hospice patients or terminally ill patients under a qualifying plan of care.2
Within those carve-outs, the NP must have the required prescriptive authority agreement and DEA registration for controlled-substance prescribing.12 The general Schedule III–V authority does not create broad hydrocodone prescribing authority outside those Texas exceptions.12