Pennsylvania

Can an NP prescribe Schedule 2 in Pennsylvania?

Chris Turitzin
Updated
March 6, 2026

Yes. In Pennsylvania, a Certified Registered Nurse Practitioner (CRNP) can prescribe Schedule II controlled substances1. A CRNP may issue up to a 30-day supply of a Schedule II medication, provided this authority is specified in the prescriptive authority collaborative agreement; Schedules III and IV may be prescribed for up to a 90-day supply when authorized in the agreement1.

Before prescribing any controlled substance, CRNPs must have DEA registration2. Additionally, when writing a controlled-substance prescription, the CRNP must include their NPI on the prescription3.

In emergencies involving a known patient, a prudent short-term controlled-substance prescription may be issued, but any emergency oral Schedule II prescription must be followed by a written prescription delivered to the pharmacist within 72 hours4. CRNPs are prohibited from prescribing or dispensing Schedule I drugs5.

Citations

  1. 49 Pa. Code § 21.284(d)(1)-(2)
  2. 49 Pa. Code § 21.284b(a)
  3. 49 Pa. Code § 21.284a(b)(2)
  4. 49 Pa. Code § 21.284b(b)(5)
  5. 49 Pa. Code § 21.284(c)(5)
Chris, founded Single Aim Health in 2024 to provide clinicians, especially NPs and PAs, with essential services for launching and growing their practices. A Stanford graduate in Product Design, Chris co-founded Momentus Media, which was acquired by Facebook, and worked as a Product Manager there. He later gained expertise in digital health through leadership roles at Bicycle Health, Virta Health, and founding Wink Health. Now, he is using his experience to help clinicians through Single Aim Health.
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