How often does a collaborative agreement need to be reviewed in Indiana?

Indiana does not set a required interval for routine, periodic review of the written collaborative practice agreement itself. Instead, the agreement must require ongoing oversight of prescribing: the physician must review the APRN’s prescribing practices weekly, and the APRN must submit documentation to the physician within seven days that includes at least a 5% random sampling of charts and medications prescribed¹.

Timely updates and oversight: Any changes to the written practice agreement—including changes in prescriptive authority—must be reported to the Board immediately². In addition, before December 31 of each even-numbered year, the Indiana professional licensing agency will randomly audit at least 1% and not more than 10% of practice agreements to verify compliance with Board requirements³.

Renewal as a practical checkpoint: While there is no mandated periodic “review” of the agreement itself, renewal cycles create natural review points. APRN licenses and prescriptive authority renew every two years, and renewal requires submitting a signed and dated written practice agreement and meeting other renewal criteria⁴⁵.