Pennsylvania CRNP collaboration uses a written collaborative agreement with a Pennsylvania-licensed physician, and CRNP prescribing uses a separate prescriptive authority collaborative agreement that is filed with the Bureau of Professional and Occupational Affairs.1 The prescriptive-authority agreement identifies the CRNP, collaborating physician, at least one substitute physician, the CRNP specialty, permitted drug categories, patient-seeing circumstances, and liability-insurance coverage.1
The Pennsylvania Department of State provides a CRNP Prescriptive Authority Collaborative Agreement Application Guide and lists CRNP prescriptive-authority forms on its Nursing Application Forms and Information page. The guide shows the PALS workflow where the CRNP starts the application, sends it to the collaborating physician, and then submits it for Board review and payment.2
Citations
1. 49 Pa. Code §§ 21.282a, 21.285.
2. Pennsylvania Department of State, CRNP Prescriptive Authority Collaborative Agreement Application Guide.
In Pennsylvania, CRNP prescriptive-authority collaboration is handled through the State Board of Nursing/PALS workflow. To obtain prescriptive authority approval, a CRNP submits the Board application and fee; the PA.gov application guide shows the CRNP starting the online application, the collaborating physician reviewing and electronically signing, and the application going to the Board for review before a printable agreement is generated.1 Pennsylvania also lists CRNP prescriptive-authority resources on its Nursing Application Forms and Information page.
The prescriptive authority collaborative agreement must be kept at the CRNP's primary practice location and a copy filed with the Bureau of Professional and Occupational Affairs.2 The CRNP must notify the Board in writing whenever the agreement is updated or terminated and, when appropriate, file the change form and amended agreement with the Board.3 PA.gov provides the change request guide and the termination form for those workflows.
Citations
1. 49 Pa. Code § 21.283(b)(2)-(3); Pennsylvania Department of State, CRNP Prescriptive Authority Collaborative Agreement Application Guide.
2. 49 Pa. Code § 21.285(a)(5).
3. 49 Pa. Code § 21.285(b); Pennsylvania State Board of Nursing, Change of Prescriptive Authority Collaborative Agreement: Termination.

⚠️ Special Note: Primary and substitute physician fees Pennsylvania prices are on the low end for the primary physician, but substitute physician coverage can add $50 to $200 per month in fees.
